FROGENT research / evaluation

Eight benchmarks. Eight task-specific definitions.

The supplied manuscript compares progressively capable systems across distinct tasks. Each family keeps its own data source, measure, and interpretation boundary.

Benchmark families

Open the task behind each result.

01Biomedical knowledge 02Known-drug retrieval 03Disease-target retrieval 04ADMET prediction 05Virtual screening 06Binding interaction profiling 07De novo molecular design 08Retrosynthesis planning

Case studies

Follow complete campaigns.

Case 01Heart-failure discovery cycle

A computational trail from disease question through target selection, molecular design, evaluation, optimization, and retrosynthesis.

Case 02Peptide optimization cycle

A design–evaluate–refine loop for peptide candidates under one consistent in silico protocol.

Case 03Small-molecule optimization cycle

Structure analysis, analogue generation, computational evaluation, and synthesis-path repair using retrieved evidence.

Evaluation figure

Read comparisons within each task family.

Values, scales, and ground truth differ by benchmark. Cross-task visual comparisons should not be interpreted as one universal measure of drug-discovery quality.

View figure

FROGENT comparison across eight task-specific benchmark families and progressively capable system variants — Supplied manuscript evaluation figure. Definitions and scales remain specific to each benchmark family.
Download source figure (PDF)